Mandible with metastatic tumout from the adrenal gland
Object numberGC.9134-1
TitleMandible with metastatic tumout from the adrenal gland
DescriptionMandible showing changes due to a metastatic cancer from the adrenal gland - an adrenal blastoma.
From a male aged 1 year, 2 months. A swelling on the right temple had been noticed, it was not pulsatile nor painful but was firm and elastic to touch and was soon complicated by slight displacement of the eyeball and swelling of the eyelid. There was progressive anaemia and the tumour became softer and of a bluish tint, and a month before death a swelling appeared over the left zygomatic bone and perforation by a right corneal ulcer caused collapse of the globe. There was considerable diurnal variation of the temperature and a yellowness of the skin preceded death from exhaustion.
On post mortem examination the right suprarenal gland was found replaced by a large, soft, purple haemorrhagic tumour, the microscopic characters of which were those of a neuroblastoma. All the bones in relation to the cephalic tumour were affected from their superficial surfaces, especially the right wing of the sphenoid and the right zygomatic one while in the right half of the mandible tumour cells had entered by the mandibular foramen and the bone had been destroyed centrifugally from the mandibular canal.
The mandible shows destruction of bone in the ramus and towards the angle. The bone has been expanded by
the tumour before destruction and has been affected from within outwards and not from the surfaces as in
the other bones
Production date 1921 - 192
Production periodTwentieth century
Object nameBONE, skull, mandible
Object categoryAnatomical, specimen
Dimensions
- Jar Height: 10.0 cm
Width: 8.7 cm
Depth: 3.8 cm