Axiell Internet Server 6 | Details | The frontal bone of a skull showing changes due to a metastatic cancer from the adrenal gland

Sidebar content	Main content
Actions	The frontal bone of a skull showing changes due to a metastatic cancer from the adrenal gland Remove from selection Add to selection Object numberGC.9134 TitleThe frontal bone of a skull showing changes due to a metastatic cancer from the adrenal gland DescriptionThe frontal bone of a skull showing changes due to a metastatic cancer from the adrenal gland - an adrenal blastoma. From a male aged 1 year, 2 months. A swelling on the right temple had been noticed, it was not pulsatile nor painful but was firm and elastic to touch and was soon complicated by slight displacement of the eyeball and swelling of the eyelid. There was progressive anaemia and the tumour became softer and of a bluish tint, and a month before death a swelling appeared over the left zygomatic bone and perforation by a right corneal ulcer caused collapse of the globe. There was considerable diurnal variation of the temperature and a yellowness of the skin preceded death from exhaustion. On post mortem examination the right suprarenal gland was found replaced by a large, soft, purple haemorrhagic tumour, the microscopic characters of which were those of a neuroblastoma. All the bones in relation to the cephalic tumour were affected from their superficial surfaces, especially the right wing of the sphenoid and the right zygomatic one while in the right half of the mandible tumour cells had entered by the mandibular foramen and the bone had been destroyed centrifugally from the mandibular canal. Description of the frontal bone: Delicate bony scales, plates, and flattened spicules ( in places assuming a honeycomb arrangement) project from the outer table of the superciliary arch, the orbital margin, the frontal squama as high as the frontal tuberosity, the zygomatic process and the temporal fossa inferior to the superior temporal line of the right half of the frontal bone, and are limited medially by the metopic suture. This new bone formation coincident with decalcification of the outer table projected into the adjacent surface of the cephalic metastasis and has continued for some distance along the orbital surface of the pars orbitalis which in two places is extensively perforated. To a less extent the inner table of the lateral part of the right pars frontalis is more or less covered with a fine shallow veneer of new bone with a somewhat radial arrangement and well defined peripherally. There is commencement of new bone formation along with decalcification of the left temporal fossa and the corresponding part of the left frontal squama on its cerebral surface. Production date 1921 - 1921 Production periodTwentieth century Object nameBONE, skull Object categoryAnatomical, specimen Dimensions Jar Height: 12.5 cm Width: 14.2 cm Depth: 6.4 cm

Object numberGC.9134

TitleThe frontal bone of a skull showing changes due to a metastatic cancer from the adrenal gland

DescriptionThe frontal bone of a skull showing changes due to a metastatic cancer from the adrenal gland - an adrenal blastoma. From a male aged 1 year, 2 months. A swelling on the right temple had been noticed, it was not pulsatile nor painful but was firm and elastic to touch and was soon complicated by slight displacement of the eyeball and swelling of the eyelid. There was progressive anaemia and the tumour became softer and of a bluish tint, and a month before death a swelling appeared over the left zygomatic bone and perforation by a right corneal ulcer caused collapse of the globe. There was considerable diurnal variation of the temperature and a yellowness of the skin preceded death from exhaustion. On post mortem examination the right suprarenal gland was found replaced by a large, soft, purple haemorrhagic tumour, the microscopic characters of which were those of a neuroblastoma. All the bones in relation to the cephalic tumour were affected from their superficial surfaces, especially the right wing of the sphenoid and the right zygomatic one while in the right half of the mandible tumour cells had entered by the mandibular foramen and the bone had been destroyed centrifugally from the mandibular canal. Description of the frontal bone: Delicate bony scales, plates, and flattened spicules ( in places assuming a honeycomb arrangement) project from the outer table of the superciliary arch, the orbital margin, the frontal squama as high as the frontal tuberosity, the zygomatic process and the temporal fossa inferior to the superior temporal line of the right half of the frontal bone, and are limited medially by the metopic suture. This new bone formation coincident with decalcification of the outer table projected into the adjacent surface of the cephalic metastasis and has continued for some distance along the orbital surface of the pars orbitalis which in two places is extensively perforated. To a less extent the inner table of the lateral part of the right pars frontalis is more or less covered with a fine shallow veneer of new bone with a somewhat radial arrangement and well defined peripherally. There is commencement of new bone formation along with decalcification of the left temporal fossa and the corresponding part of the left frontal squama on its cerebral surface.

Production date 1921 - 1921

Production periodTwentieth century

Object nameBONE, skull

Object categoryAnatomical, specimen

Dimensions

Item request date
Expected return date
Destination