Liver, melanomatosis
Object numberGC.7817
TitleLiver, melanomatosis
Creator James DAVIDSON
DescriptionWet specimen.
Portion of a liver, showing melanomatosis.
From a female aged 64 years, feeble and emaciated, whose symptoms, sickness and vomiting and enlargement of the liver suggested carcinoma of the stomach. Eighteen months previously the left eye had been enucleated for melanoma of the chorioid. Post mortem examination showed the liver greatly enlarged by melanomatosis. No other viscus contained metastasis.
Throughout the liver are innumerable melanotic patches, more or less circular and varying in size to some 10 mm. in diameter. The surface of the liver is smooth and there is no thickening of the capsule. A quadrilateral portion of the liver at the periphery is conspicuously devoid of pigmented areas and instead has a mottled yellowish appearance. Microscopic examination shows considerable necrosis of the hepatic parenchyma and the tumour tissue is ill defined. Outwith the neoplasmic area the hepatic parenchyma is fibrous (cirrhosed) and necrotic, with evident bile ducts.
Production date 1929
Production periodTwentieth century, mid
Object nameLIVER
Object categoryAnatomical, specimen