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Actions	Penis with condylamata Remove from selection Add to selection Object numberGC.11905 TitlePenis with condylamata DescriptionPenis - Condylomata. Clinical history: From a male aged 39 years. The patient first noticed “warts on the penis in 1946. Circumcised in 1954 at Catterick Military Hospital. The condition gradually became worse and he received treatment with podophyllin (and probably also cauterisation) intermittently between 1956 and 1957. Condition on examination Large fungating warty mass replacing most of glans penis and involving the remains of the prepuce. The urinary meatus is visible but the warty growth encircles this. No sessile warts protrude from the meatus and there is no intrameatal involvement and no obstruction of urinary flow. Inguinal glands not enlarged to noteworthy extent. Wassermann reaction and Kahn test “negative”. Biopsy done on three separate occasions - no evidence of malignancy found. Multiple sinuses developed with discharge of foul pus which contained a mixture of organisms including Ps. Pyocyaneus. Treatment with antibiotics produced a temporary improvement. Repeated attempts were made to remove all warty tissue by curette, diathermy and electrocautery. Rapid formation of new masses almost as large as the original growth occurred. Amputation advised and performed. Description of specimen: In section much of the epithelium has been lost in preparation. There is a very great deal of fibrosis in the subepithelial layer and in this there is no evidence whatsoever of any epithelial invasion. On the surface immediately below the epithelium, fibrous tissue is laid down in strands which intersect and leave spaces between the different areas. In some areas fibrous masses - strands project on the surface and may well have been the core of the papillomata. The epithelium itself shows some degree of thickening but there is little full keratin formation. Beneath the epithelium there is inflammatory cell infiltration. Microscopical report This specimen illustrates how closely an infective condyloma can simulate malignant disease - a condition sometimes called “Buschke - Loewenstein Tumours”. The differentiation can be made solely by repeated histological examination. Production date 1958 Object namePENIS Object categoryAnatomical, specimen Dimensions container Height: 7.5 cm Length: 9 cm Width: 9 cm

Object numberGC.11905

TitlePenis with condylamata

DescriptionPenis - Condylomata. Clinical history: From a male aged 39 years. The patient first noticed “warts on the penis in 1946. Circumcised in 1954 at Catterick Military Hospital. The condition gradually became worse and he received treatment with podophyllin (and probably also cauterisation) intermittently between 1956 and 1957. Condition on examination Large fungating warty mass replacing most of glans penis and involving the remains of the prepuce. The urinary meatus is visible but the warty growth encircles this. No sessile warts protrude from the meatus and there is no intrameatal involvement and no obstruction of urinary flow. Inguinal glands not enlarged to noteworthy extent. Wassermann reaction and Kahn test “negative”. Biopsy done on three separate occasions - no evidence of malignancy found. Multiple sinuses developed with discharge of foul pus which contained a mixture of organisms including Ps. Pyocyaneus. Treatment with antibiotics produced a temporary improvement. Repeated attempts were made to remove all warty tissue by curette, diathermy and electrocautery. Rapid formation of new masses almost as large as the original growth occurred. Amputation advised and performed. Description of specimen: In section much of the epithelium has been lost in preparation. There is a very great deal of fibrosis in the subepithelial layer and in this there is no evidence whatsoever of any epithelial invasion. On the surface immediately below the epithelium, fibrous tissue is laid down in strands which intersect and leave spaces between the different areas. In some areas fibrous masses - strands project on the surface and may well have been the core of the papillomata. The epithelium itself shows some degree of thickening but there is little full keratin formation. Beneath the epithelium there is inflammatory cell infiltration. Microscopical report This specimen illustrates how closely an infective condyloma can simulate malignant disease - a condition sometimes called “Buschke - Loewenstein Tumours”. The differentiation can be made solely by repeated histological examination.

Production date 1958

Object namePENIS

Object categoryAnatomical, specimen

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